Welcome to the website of the TMF Reference Model. The TMF Reference Model was developed under the auspices of the Drug Information Association (DIA) Document and Records Management Community and is now affiliated to the Clinical Data Interchange Standards Consortium (CDISC).

The TMF Reference Model provides standardized taxonomy and metadata and outlines a reference definition of TMF content using standard nomenclature. The Model is not intended to be taken and used “off-the-shelf” but can be adapted to an electronic or paper TMF, and does not endorse, nor require, any specific technology for application. Organizations are under no obligation to adopt the TMF Reference Model.