TMF Reference Model v3.1, Released 10-SEP-2018, Superseded 02-Nov-2020
TMF Reference Model v3.0, Released 16-JUN-2015, Superseded 10-SEP-2018
TMF Reference Model v2.0, Released 25-JUN-2012, Superseded 16-JUN-2015
TMF Reference Model v1.2, Released 02-DEC-2011, Superseded 25-JUN-2012
TMF Reference Model v1.1, Released 11-FEB-2011, Superseded 02-DEC-2011
TMF Reference Model v1.0, Released 04-JUN-2010, Superseded 11-FEB-2011
November 12, 2018
September 10, 2018
May 14, 2018
March 19, 2018
January 22, 2018
November 6, 2017
September 11, 2017
June 12, 2017
April 24, 2017
February 27, 2017
January 9, 2017
Meeting recordings (where available) can be accessed on our YouTube channel: click HERE
MindJet File for TMF-RM v3.0 (.mmap format – requires MindJet licence to open file or MindManager Viewer to view file)
MindMap PDF File for TMF-RM v3.0 (.pdf format – requires Acrobat Reader and Adobe Flash)
eTMF-EMS Specification v1.0.1 Released 25-OCT-2019
eTMF-EMS Release Notes r19.3.2 25-OCT-2019
eTMF-EMS Release Notes r19.1.5
eTMF-EMS Specification v1.0, Released 14-JUN-2018
XML Exchange Structure (hosted on GitHub)
eTMF-EMS Launch Presentation at DIA Global 22-JUN-2018 (PowerPoint)
TMF Plan Template v1: Suggested structure and outline for a Trial Master File Plan (v1.0 Approved 23-February 2018)
The following are now incorporated into the TMF Reference Model:
– Milestones / Events: Suggested latest milestones or events by which each artifact should be filed (v1.1 Approved 31-January-2018)
– Date Conventions: Suggested date convention to use for each artifact (Approved 15-Feb-2017)
2014 TMF Survey Overview (PDF File)
2013 TMF Survey Overview (PDF File)
2012 TMF Survey Overview (PDF File)
2016 Project Team Roadmap
DIA Framework for the Destruction of Paper Originals v2.0 (23-Jan-2019)
Presentation – Framework for Paper Destruction (May 2012)
Process Map – Processes used in TMF Reference Model (July 2011)
TMF Reference Model Standard = Process Efficiency (published Applied Clinical Trials, May 2014)
TMF Reference Model Presentation: Overview of the TMF Reference Model, Published August 2012