I’m looking to determine whether there is a centralized source or reference database available that maps Trial Master File (TMF) artifacts to the Investigator Site File (ISF). If such a resource exists, I would greatly appreciate any guidance or direction you could provide.
What you’re asking is already built into the Reference Model. Per the regulations, the TMF includes both the sponsor essential records and the investigator essential records (aka ISF). Just filter the spreadsheet for “Investigator Site) to see the ISF.
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